Multifunctional mesoporous silica-cerium oxide nanozymes facilitate miR129 delivery for high-quality healing of radiation-induced skin injury

Multifunctional mesoporous silica-cerium oxide nanozymes facilitate miR129 delivery for high-quality healing of radiation-induced skin injury

Abstract Radiation-induced skin injury (RISI) is an important challenge for clinical treatments. The main causes of RISI include hypoxia in the wound microenvironment, reactive oxygen species (ROS) activation, and downregulation of DNA repair proteins. Here, a multiple radioresistance strategy was d...

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Bibliographic Details
Main Authors: Daijun Zhou, Min Du, Han Luo, Fengwei Ran, Xiang Zhao, Yan Dong, Tao Zhang, Jie Hao, Dong Li, Jianjun Li
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Nanobiotechnology
Subjects:
Mesoporous silica
CeO2
miRNA-129
Radiation-induced skin injury
Online Access:https://doi.org/10.1186/s12951-022-01620-5

Internet

https://doi.org/10.1186/s12951-022-01620-5

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