The Choroid Plexus Functions as a Niche for T-Cell Stimulation Within the Central Nervous System

The Choroid Plexus Functions as a Niche for T-Cell Stimulation Within the Central Nervous System

The choroid plexus (CP) compartment in the ventricles of the brain comprises fenestrated vasculature and, therefore, it is permeable to blood-borne mediators of inflammation. Here, we explored whether T-cell activation in the CP plays a role in regulating central nervous system (CNS) inflammation. W...

Full description

Bibliographic Details
Main Authors: Itai Strominger, Yehezqel Elyahu, Omer Berner, Jensen Reckhow, Kritika Mittal, Anna Nemirovsky, Alon Monsonego
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
central nervous system
choroid plexus
cerebrospinal fluid
CD4 T cell
antigen-presenting cell
migration
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.01066/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.01066/full

Similar Items