Sinapic acid attenuates cyclophosphamide-induced liver toxicity in mice by modulating oxidative stress, NF-κB, and caspase-3

Sinapic acid attenuates cyclophosphamide-induced liver toxicity in mice by modulating oxidative stress, NF-κB, and caspase-3

Objective(s): Cyclophosphamide (CP) as an antineoplastic drug is widely used in cancer patients, and liver toxicity is one of its complications. Sinapic acid (SA) as a natural phenylpropanoid has anti-oxidant, anti-inflammatory, and anti-cancer properties.Materials and Methods: The purpose of the cu...

Full description

Bibliographic Details
Main Authors: Shiva Rezaei, Seyed Jalal Hosseinimehr, Mehryar Zargari, Abbasali Karimpour Malekshah, Mansooreh Mirzaei, Fereshteh Talebpour Amiri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
apoptosis
cyclophosphamide
liver injury
inflammation
oxidative stress
sinapic acid
Online Access:https://ijbms.mums.ac.ir/article_21867_640ba41bd3e67e10925558219f9f8e34.pdf

Internet

https://ijbms.mums.ac.ir/article_21867_640ba41bd3e67e10925558219f9f8e34.pdf

Similar Items