Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS

Background The enterosalivary nitrate–nitrite–nitric oxide (NO3–NO2–NO) pathway generates NO following oral microbiota‐mediated production of salivary nitrite, potentially linking the oral microbiota to reduced cardiometabolic risk. Nitrite depletion by oral bacteria may also be important for determ...

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Bibliographic Details
Main Authors: Charlene E. Goh, Bruno Bohn, Clarisse Marotz, Rebecca Molinsky, Sumith Roy, Bruce J. Paster, Ching‐Yuan Chen, Michael Rosenbaum, Melana Yuzefpolskaya, Paolo C. Colombo, Moïse Desvarieux, Panos N. Papapanou, David R. Jacobs, Rob Knight, Ryan T. Demmer
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
16S rNA sequencing
blood pressure
epidemiology
insulin resistance
metagenomics
nitric oxide
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.023038

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.121.023038

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