Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS
Background The enterosalivary nitrate–nitrite–nitric oxide (NO3–NO2–NO) pathway generates NO following oral microbiota‐mediated production of salivary nitrite, potentially linking the oral microbiota to reduced cardiometabolic risk. Nitrite depletion by oral bacteria may also be important for determ...
Main Authors: | Charlene E. Goh, Bruno Bohn, Clarisse Marotz, Rebecca Molinsky, Sumith Roy, Bruce J. Paster, Ching‐Yuan Chen, Michael Rosenbaum, Melana Yuzefpolskaya, Paolo C. Colombo, Moïse Desvarieux, Panos N. Papapanou, David R. Jacobs, Rob Knight, Ryan T. Demmer |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-05-01
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Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
Subjects: | |
Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.121.023038 |
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