GC–MS and LC-TOF–MS profiles, toxicity, and macrophage-dependent in vitro anti-osteoporosis activity of Prunus africana (Hook f.) Kalkman Bark

GC–MS and LC-TOF–MS profiles, toxicity, and macrophage-dependent in vitro anti-osteoporosis activity of Prunus africana (Hook f.) Kalkman Bark

Abstract Osteoporosis affects millions of people worldwide. As such, this study assessed the macrophage-dependent in vitro anti-osteoporosis, phytochemical profile and hepatotoxicity effects in zebrafish larvae of the stem bark extracts of P. africana. Mouse bone marrow macrophages (BMM) cells were...

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Bibliographic Details
Main Authors: Richard Komakech, Ki-Shuk Shim, Nam-Hui Yim, Jun Ho Song, Sungyu Yang, Goya Choi, Jun Lee, Yong-goo Kim, Francis Omujal, Denis Okello, Moses Solomon Agwaya, Grace Nambatya Kyeyune, Hyemin Kan, Kyu-Seok Hwang, Motlalepula Gilbert Matsabisa, Youngmin Kang
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10629-7

Internet

https://doi.org/10.1038/s41598-022-10629-7

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