Review: Omalizumab in the treatment of severe asthma: efficacy and current problems

Omalizumab is a humanized monoclonal anti-IgE antibody recently approved for the treatment of severe allergic asthma. This drug inhibits allergic responses by binding to serum IgE, thus preventing their interactions with cellular IgE receptors. Omalizumab is also capable of downregulating the expres...

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Bibliographic Details
Main Authors: Girolamo Pelaia, Teresa Renda, Pasquale Romeo, Maria Teresa Busceti, Rosario Maselli
Format: Article
Language:English
Published: SAGE Publishing 2008-12-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465808100431