Efficient Generation of Multiple Seamless Point Mutations Conferring Triazole Resistance in <i>Aspergillus fumigatus</i>

Efficient Generation of Multiple Seamless Point Mutations Conferring Triazole Resistance in <i>Aspergillus fumigatus</i>

<i>Aspergillus fumigatus</i> is a common human fungal pathogen that can cause a range of diseases. Triazoles are used to treat <i>A. fumigatus</i> infections, but resistance is increasing due to mutations in genes such as <i>cyp51A</i>, <i>hmg1</i> and...

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Bibliographic Details
Main Authors: Mariana Handelman, Nir Osherov
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Fungi
Subjects:
<i>Aspergillus fumigatus</i>
CRISPR-Cas9
ARMS-PCR
pTel
genetic manipulation
Online Access:https://www.mdpi.com/2309-608X/9/6/644

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https://www.mdpi.com/2309-608X/9/6/644

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