Nuclear complement C3b promotes paclitaxel resistance by assembling the SIN3A/HDAC1/2 complex in non-small cell lung cancer

Nuclear complement C3b promotes paclitaxel resistance by assembling the SIN3A/HDAC1/2 complex in non-small cell lung cancer

Abstract In addition to the classical role as a serum effector system of innate immunity, accumulating evidence suggests that intracellular complement components have indispensable functions in immune defense, T cell homeostasis, and tumor cell proliferation and metastasis. Here, we revealed that co...

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Main Authors: Xiaochao Wang, Yan Hao, Jianfeng Chen, Peipei Ding, Xinyue Lv, Danlei Zhou, Ling Li, Luying Li, Yanqing Xu, Yumeng Zhu, Wei Zhang, Lu Chen, Tian Liao, Xianghuo He, Qing-Hai Ji, Weiguo Hu
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05869-y

Internet

https://doi.org/10.1038/s41419-023-05869-y

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