Phosphatidylinositol 4,5-Bisphosphate Mediates the Co-Distribution of Influenza A Hemagglutinin and Matrix Protein M1 at the Plasma Membrane

Phosphatidylinositol 4,5-Bisphosphate Mediates the Co-Distribution of Influenza A Hemagglutinin and Matrix Protein M1 at the Plasma Membrane

The fully assembled influenza A virus (IAV) has on its surface the highest density of a single membrane protein found in nature—the glycoprotein hemagglutinin (HA) that mediates viral binding, entry, and assembly. HA clusters at the plasma membrane of infected cells, and the HA density (number of mo...

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Bibliographic Details
Main Authors: Prakash Raut, Bright Obeng, Hang Waters, Joshua Zimmerberg, Julie A. Gosse, Samuel T. Hess
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
influenza A
super-resolution fluorescence microscopy
host–virus interactions
matrix protein M1
phosphoinositides
PIP2
Online Access:https://www.mdpi.com/1999-4915/14/11/2509

Internet

https://www.mdpi.com/1999-4915/14/11/2509

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