Dexamethasone Promotes <i>Aspergillus fumigatus</i> Growth in Macrophages by Triggering M2 Repolarization via Targeting PKM2

Dexamethasone Promotes <i>Aspergillus fumigatus</i> Growth in Macrophages by Triggering M2 Repolarization via Targeting PKM2

Since long-term corticosteroid treatment is associated with emerging opportunistic fungal infections causing high morbidity and mortality in immune-suppressed individuals, here we characterized the impact of dexamethasone (Dex) treatment on <i>Aspergillus fumigatus</i>-related immune mod...

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Bibliographic Details
Main Authors: Maureen K. Luvanda, Wilfried Posch, Jonathan Vosper, Viktoria Zaderer, Asma Noureen, Cornelia Lass-Flörl, Doris Wilflingseder
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Journal of Fungi
Subjects:
glucocorticoids
dexamethasone
macrophages
glycolytic pathway
PKM2
<i>Aspergillus fumigatus</i>
Online Access:https://www.mdpi.com/2309-608X/7/2/70

Internet

https://www.mdpi.com/2309-608X/7/2/70

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