Polymeric Micelles Enhance Mucosal Contact Time and Deposition of Fluocinolone Acetonide

Polymeric Micelles Enhance Mucosal Contact Time and Deposition of Fluocinolone Acetonide

This study used polymeric micelles to improve quality by increasing drug solubility, extending mucosal drug retention time, enhancing mucoadhesiveness, and promoting drug permeation and deposition. Fluocinolone acetonide (FA) was loaded into polymeric micelles (FPM), which were composed of poloxamer...

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Bibliographic Details
Main Authors: Sucharat Limsitthichaikoon, Siriwat Soontaranon, Nuntachai Hanpramukkun, Kanjana Thumanu, Aroonsri Priprem
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Polymers
Subjects:
drug–mucin contact time
focal plane array (FPA)-based Fourier transform infrared (FTIR) imaging
hydrophobic drug
mouth rinse
polymeric micelles
Online Access:https://www.mdpi.com/2073-4360/14/11/2247

Internet

https://www.mdpi.com/2073-4360/14/11/2247

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