Forkhead box protein 1 transcriptionally activates sestrin1 to alleviate oxidized low-density lipoprotein-induced inflammation and lipid accumulation in macrophages

Forkhead box protein 1 transcriptionally activates sestrin1 to alleviate oxidized low-density lipoprotein-induced inflammation and lipid accumulation in macrophages

Transcription factor forkhead box protein 1 (FOXP1) has been shown cardiovascular protection. We aimed to analyze the role of FOXP1 in oxidized low-density lipoprotein (ox-LDL)-induced macrophages and its possible regulatory effect on sestrin1 (SESN1) expression. After stimulation with ox-LDL, FOXP1...

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Bibliographic Details
Main Authors: Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou
Format: Article
Language:English
Published: Taylor & Francis Group 2022-02-01
Series:Bioengineered
Subjects:
atherosclerosis
inflammation
lipid accumulation
foxp1
sesn1
Online Access:http://dx.doi.org/10.1080/21655979.2021.2000228

Internet

http://dx.doi.org/10.1080/21655979.2021.2000228

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