Computational modeling of chromatin accessibility identified important epigenomic regulators

Computational modeling of chromatin accessibility identified important epigenomic regulators

Abstract Chromatin accessibility is essential for transcriptional activation of genomic regions. It is well established that transcription factors (TFs) and histone modifications (HMs) play critical roles in chromatin accessibility regulation. However, there is a lack of studies that quantify these...

Full description

Bibliographic Details
Main Authors: Yanding Zhao, Yadong Dong, Wei Hong, Chongming Jiang, Kevin Yao, Chao Cheng
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Genomics
Subjects:
ENCODE
Chromatin accessibility
Histone modifications
Transcription factor
Machine learning
Online Access:https://doi.org/10.1186/s12864-021-08234-5

Internet

https://doi.org/10.1186/s12864-021-08234-5

Similar Items