Development, optimization and pharmacokinetic evaluation of biphasic extended-release osmotic drug delivery system of trospium chloride for promising application in treatment of overactive bladder

Development, optimization and pharmacokinetic evaluation of biphasic extended-release osmotic drug delivery system of trospium chloride for promising application in treatment of overactive bladder

Abstract Background The research was aimed with an approach to formulate biphasic extended-release system of trospium chloride resulting in controlled release of drug up to 24 h with prospects of better control on urinary frequency, efficacy, tolerability, and improved patient compliance. The push–p...

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Bibliographic Details
Main Authors: Ramakanth Gundu, Sanjay Pekamwar, Santosh Shelke, Deepak Kulkarni, Santosh Shep
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Trospium chloride
Push–pull osmotic pump
Drug release
Pharmacokinetic
Overactive bladder
Online Access:https://doi.org/10.1186/s43094-021-00311-6

Internet

https://doi.org/10.1186/s43094-021-00311-6

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