Extending the “One Strain Many Compounds” (OSMAC) Principle to Marine Microorganisms

Extending the “One Strain Many Compounds” (OSMAC) Principle to Marine Microorganisms

Genomic data often highlights an inconsistency between the number of gene clusters identified using bioinformatic approaches as potentially producing secondary metabolites and the actual number of chemically characterized secondary metabolites produced by any given microorganism. Such gene clusters...

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Bibliographic Details
Main Authors: Stefano Romano, Stephen A. Jackson, Sloane Patry, Alan D. W. Dobson
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Marine Drugs
Subjects:
secondary metabolites
biosynthetic gene clusters
cultivation
environmental cues
co-cultivation
chemical elicitors
one strain many compounds
OSMAC
Online Access:http://www.mdpi.com/1660-3397/16/7/244

Internet

http://www.mdpi.com/1660-3397/16/7/244

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