Enhancement of Radiation Therapy through Blockade of the Immune Checkpoint, V-domain Ig Suppressor of T Cell Activation (VISTA), in Melanoma and Adenocarcinoma Murine Models

Enhancement of Radiation Therapy through Blockade of the Immune Checkpoint, V-domain Ig Suppressor of T Cell Activation (VISTA), in Melanoma and Adenocarcinoma Murine Models

Radiation therapy (RT) has recently demonstrated promise at stimulating an enhanced immune response. The recent success of immunotherapies, such as checkpoint inhibitors, CART cells, and other immune modulators, affords new opportunities for combination with radiation. The aim of this study is to ev...

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Bibliographic Details
Main Authors: Kayla E. A. Duval, Armin D. Tavakkoli, Alireza Kheirollah, Haille E. Soderholm, Eugene Demidenko, Janet L. Lines, Walburga Croteau, Samuel C. Zhang, Robert J. Wagner, Ethan Aulwes, Randolph J. Noelle, P. Jack Hoopes
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
checkpoint inhibitor
VISTA
radiation therapy
Online Access:https://www.mdpi.com/1422-0067/24/18/13742

Internet

https://www.mdpi.com/1422-0067/24/18/13742

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