Impact of protein and small molecule interactions on kinase conformations

Protein kinases act as central molecular switches in the control of cellular functions. Alterations in the regulation and function of protein kinases may provoke diseases including cancer. In this study we investigate the conformational states of such disease-associated kinases using the high sensit...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Valentina Kugler, Selina Schwaighofer, Andreas Feichtner, Florian Enzler, Jakob Fleischmann, Sophie Strich, Sarah Schwarz, Rebecca Wilson, Philipp Tschaikner, Jakob Troppmair, Veronika Sexl, Pascal Meier, Teresa Kaserer, Eduard Stefan
التنسيق: مقال
اللغة:English
منشور في: eLife Sciences Publications Ltd 2024-08-01
سلاسل:eLife
الموضوعات:
الوصول للمادة أونلاين:https://elifesciences.org/articles/94755