Platelet-derived growth factor-BB pretreatment attenuates excitotoxic death in cultured hippocampal neurons
Neuronal excitotoxic death results from excess stimulation by elevated levels of extracellular glutamate acting on N-methyl-d-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. While excitotoxicity is typically attenuated by using glutamate receptor antagonis...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2005-06-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996104002803 |