Epigenetic regulation of ID4 in breast cancer: tumor suppressor or oncogene?

Abstract Background Inhibitor of differentiation protein 4 (ID4) is a dominant negative regulator of the basic helix-loop-helix (bHLH) family of transcription factors. During tumorigenesis, ID4 may act as a tumor suppressor or as an oncogene in different tumor types. However, the role of ID4 in brea...

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Bibliographic Details
Main Authors: Daniela Nasif, Emanuel Campoy, Sergio Laurito, Richard Branham, Guillermo Urrutia, María Roqué, María T. Branham
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13148-018-0542-8