DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination

DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.

Bibliographic Details
Main Authors: Prasun Chakraborty, Kevin Hiom
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24341-z