Nanosuspensions and Microneedles Roller as a Combined Approach to Enhance Diclofenac Topical Bioavailability

Topical application of the anti-inflammatory drug diclofenac (DCF) reduces the severity of systemic unwanted effects compared to its oral administration. A number of transdermal formulations are available on the market and routinely used in clinical and home-care settings. However, the amount of DCF...

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Bibliographic Details
Main Authors: Rosa Pireddu, Michele Schlich, Salvatore Marceddu, Donatella Valenti, Elena Pini, Anna Maria Fadda, Francesco Lai, Chiara Sinico
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/12/1140