DNA hypermethylation: A novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction

DNA hypermethylation: A novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction

Objective: Cellular repressor of E1A-stimulated genes (CREG), a vasculoprotective molecule, is significantly downregulated in atherosclerotic vessels through unclear mechanisms. While epigenetic regulation is involved in atherosclerosis development, it is not known if the CREG gene is epigenetically...

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Bibliographic Details
Main Authors: Yanxia Liu, Xiaoxiang Tian, Shan Liu, Dan Liu, Yang Li, Meili Liu, Xiaolin Zhang, Chenghui Yan, Yaling Han
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Redox Biology
Subjects:
Epigenetics
CREG
Atherosclerosis
Endothelium
Nitric oxide
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719313977

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http://www.sciencedirect.com/science/article/pii/S2213231719313977

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