Major Challenges and Potential Microenvironment-Targeted Therapies in Glioblastoma

Major Challenges and Potential Microenvironment-Targeted Therapies in Glioblastoma

Glioblastoma (GBM) is considered one of the most malignant, genetically heterogeneous, and therapy-resistant solid tumor. Therapeutic options are limited in GBM and involve surgical resection followed by chemotherapy and/or radiotherapy. Adjuvant therapies, including antiangiogenic treatments (AATs)...

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Bibliographic Details
Main Authors: Ali S. Arbab, Mohammad H. Rashid, Kartik Angara, Thaiz F. Borin, Ping-Chang Lin, Meenu Jain, Bhagelu R. Achyut
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
tumor microenvironment
Glioblastoma
neovascularization
antiangiogenic therapy
resistance
bone marrow-derived cells
myeloid cells
Online Access:https://www.mdpi.com/1422-0067/18/12/2732

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https://www.mdpi.com/1422-0067/18/12/2732

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