Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseases

Abstract As global aging accelerates, the prevention and treatment of age-related bone diseases are becoming a critical issue. In the process of senescence, bone marrow mesenchymal stem cells (BMSCs) gradually lose the capability of self-renewal and functional differentiation, resulting in impairmen...

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Bibliographic Details
Main Authors: Yi Zhao, Jiawei He, Tao Qiu, Haoyu Zhang, Li Liao, Xiaoxia Su
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-02852-w