PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

ABSTRACT Stimulator of interferon genes (STING) is an essential adaptor protein of the innate DNA-sensing signaling pathway, which recognizes genomic DNA from invading pathogens to establish antiviral responses in host cells. STING activity is tightly regulated by several posttranslational modificat...

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Bibliographic Details
Main Authors: Guoxin Ni, Zhe Ma, Jason P. Wong, Zhigang Zhang, Emily Cousins, M. Ben Major, Blossom Damania
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
PPP6C
STING
phosphorylation
phosphatase
interferon
KSHV
Online Access:https://journals.asm.org/doi/10.1128/mBio.01728-20

Internet

https://journals.asm.org/doi/10.1128/mBio.01728-20

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