Nonlinear physics opens a new paradigm for accurate transcription start site prediction

Abstract There is evidence that DNA breathing (spontaneous opening of the DNA strands) plays a relevant role in the interactions of DNA with other molecules, and in particular in the transcription process. Therefore, having physical models that can predict these openings is of interest. However, thi...

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Bibliographic Details
Main Authors: José Antonio Barbero-Aparicio, Santiago Cuesta-Lopez, César Ignacio García-Osorio, Javier Pérez-Rodríguez, Nicolás García-Pedrajas
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-05129-4