Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes
Finding the ideal epitope to target is a key element for the development of an antibody-drug conjugate (ADC). To maximize drug delivery to tumor cells and reduce side effects, this epitope should be specific to cancer cells and spare all normal tissue. During cancer progression, glycosylation pathwa...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
IMR Press
2022-11-01
|
Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/27/11/10.31083/j.fbl2711301 |