Timing of antibiotic administration determines the spread of plasmid-encoded antibiotic resistance during microbial range expansion

Abstract Plasmids are the main vector by which antibiotic resistance is transferred between bacterial cells within surface-associated communities. In this study, we ask whether there is an optimal time to administer antibiotics to minimize plasmid spread in new bacterial genotypes during community e...

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Bibliographic Details
Main Authors: Yinyin Ma, Josep Ramoneda, David R. Johnson
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39354-z