Altered gut microbiome plays an important role in AKI to CKD transition in aged mice

Altered gut microbiome plays an important role in AKI to CKD transition in aged mice

IntroductionThis study investigated the role of renal-intestinal crosstalk in the transition from acute kidney injury (AKI) to chronic kidney disease (CKD) in elderly individuals.MethodsUsing young and aged mice, we induced bilateral ischemia-reperfusion injury (IRI) and compared intestinal and kidn...

Full description

Bibliographic Details
Main Authors: Myung-Gyu Kim, Won Yong Cho, Suk Min Chung, Young Eun Choi, Yina Fang, Myeong Soo Park, Sang Jun Park, Yoon Sook Ko, Hee Young Lee, Jihyun Yang, Se Won Oh, Sang-Kyung Jo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Medicine
Subjects:
aging
acute kidney injury
chronic kidney disease
microbiome
chronic inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1238960/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1238960/full

Similar Items