Down-regulation of miR-4443/TIMP2 signaling pathway enhances sorafenib sensitivity in HepG2 cells

Down-regulation of miR-4443/TIMP2 signaling pathway enhances sorafenib sensitivity in HepG2 cells

Objective To investigate the significance of down-regulating the miR-4443/TIMP2 pathway on sorafenib sensitivity in HepG2 cells. Methods HepG2 cells were divided into control group (DMSO) and sorafenib treatment group (10 μmol/L). After treatment for 24 h, the mRNA level of miR-4443 was measured by...

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Bibliographic Details
Main Authors: XIAO Hanxi, ZHANG Yueting, SUN Liangbo, LI Tao, CHEN Lingxi, YAN Xiaojing, HE Fengtian, LIAN Jiqin
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-02-01
Series:Di-san junyi daxue xuebao
Subjects:
sorafenib
hepg2 cells
mir-4443
timp2
drug resistance
Online Access:https://aammt.tmmu.edu.cn/Upload/rhtml/202008219.htm

Internet

https://aammt.tmmu.edu.cn/Upload/rhtml/202008219.htm

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