Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration

Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration

Dysfunction of retinal neurons is a major cause of vision impairment in blinding diseases that affect children and adults worldwide. Cellular damage resulting from polyamine catabolism has been demonstrated to be a major player in many neurodegenerative conditions. We have previously shown that inhi...

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Bibliographic Details
Main Authors: Prahalathan Pichavaram, Chithra Devi Palani, Chintan Patel, Zhimin Xu, Esraa Shosha, Abdelrahman Y. Fouda, Ruth B. Caldwell, Subhadra Priya Narayanan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neuroscience
Subjects:
retina
neurodegeneration
excitotoxicity
polyamine oxidase
MDL 72527
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00956/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00956/full

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