Liposome-encapsulated curcumin attenuates HMGB1-mediated hepatic inflammation and fibrosis in a murine model of Wilson’s disease

Background and aims: Wilson’s disease (WD) is an inherited disorder of copper metabolism with predominant hepatic manifestations. Left untreated, it can be fatal. Current therapies focus on treating copper overload rather than targeting the pathophysiology of copper-induced liver injuries. We sought...

Full description

Bibliographic Details
Main Authors: Wai-In Ho, Yang Hu, Chi-Wa Cheng, Rui Wei, Jiayin Yang, Na Li, Ka-Wing Au, Yiu-Lam Tse, Qiuyun Wang, Kwong-Man Ng, Miguel A. Esteban, Hung-Fat Tse
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222005868