Buprenorphine reduces methamphetamine intake and drug seeking behavior via activating nociceptin/orphanin FQ peptide receptor in rats

Buprenorphine reduces methamphetamine intake and drug seeking behavior via activating nociceptin/orphanin FQ peptide receptor in rats

Buprenorphine, which has been approved for the treatment of opioid dependence, reduces cocaine consumption by co-activating μ-opioid receptors and nociceptin/orphanin FQ peptide (NOP) receptors. However, the role of buprenorphine in methamphetamine (METH) reinforcement and drug-seeking behavior rema...

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Bibliographic Details
Main Authors: Fangmin Wang, Wenwen Shen, Yujia Cai, Xin Zhang, Han Du, Miaojun Lai, Huifen Liu, Evelyne Kohli, Wenhua Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Psychiatry
Subjects:
buprenorphine
nociceptin/orphanin FQ peptide
substance use disorder
opioid receptor
methamphetamine
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.983595/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2022.983595/full

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