Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma

Abstract Although glaucoma is a disease modulated by eye pressure, the mechanisms of pressure sensing in the eye are not well understood. Here, we investigated associations between mechanosensitive ion channel gene variants and primary open-angle glaucoma (POAG). Common (minor allele frequency > ...

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Bibliographic Details
Main Authors: Wendy W. Liu, Tyler G. Kinzy, Jessica N. Cooke Bailey, Zihe Xu, Pirro Hysi, Janey L. Wiggs, NEIGHBORHOOD Consortium
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43072-3