Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception

Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception

Hedgehog (Hh) signaling patterns embryonic tissues and contributes to homeostasis in adults. In Drosophila, Hh transport and signaling are thought to occur along a specialized class of actin-rich filopodia, termed cytonemes. Here, we report that Interference hedgehog (Ihog) not only forms a Hh recep...

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Bibliographic Details
Main Authors: Shu Yang, Ya Zhang, Chuxuan Yang, Xuefeng Wu, Sarah Maria El Oud, Rongfang Chen, Xudong Cai, Xufeng S Wu, Ganhui Lan, Xiaoyan Zheng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
Hedgehog signaling
trans-homophilic binding
cytoneme
dual role
Online Access:https://elifesciences.org/articles/65770

Internet

https://elifesciences.org/articles/65770

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