Causal relationship between the blood immune cells and intervertebral disc degeneration: univariable, bidirectional and multivariable Mendelian randomization

BackgroundIntervertebral disc degeneration (IVDD) is a prominent contributor to chronic low back pain, impacting millions of individuals annually. Current research on disc degeneration is placing a growing emphasis on the role of the immune system in this process. Nevertheless, the precise relations...

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Bibliographic Details
Main Authors: Chaofan Qin, Mingxin Chen, Qingshuai Yu, Xin Wang, Tao Hu, Bo Lei, Zhengjian Yan, Si Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1321295/full