The Ionophores CCCP and Gramicidin but Not Nigericin Inhibit <i>Trypanosoma brucei</i> Aquaglyceroporins at Neutral pH
Human African trypanosomiasis (HAT) is caused by <i>Trypanosoma brucei</i> parasites. The <i>T. brucei</i> aquaglyceroporin isoform 2, TbAQP2, has been linked to the uptake of pentamidine. Negative membrane potentials and transmembrane pH gradients were suggested to promote t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/9/10/2335 |