SH3-Binding Glutamic Acid Rich-Deficiency Augments Apoptosis in Neonatal Rat Cardiomyocytes

SH3-Binding Glutamic Acid Rich-Deficiency Augments Apoptosis in Neonatal Rat Cardiomyocytes

Congenital heart disease (CHD) is one of the most common birth defects in humans, present in around 40% of newborns with Down’s syndrome (DS). The SH3 domain-binding glutamic acid-rich (SH3BGR) gene, which maps to the DS region, belongs to a gene family encoding a cluster of small thioredoxin-like p...

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Bibliographic Details
Main Authors: Anushka Deshpande, Ankush Borlepawar, Alexandra Rosskopf, Derk Frank, Norbert Frey, Ashraf Yusuf Rangrez
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
SH3BGR
cardiac hypertrophy
SRF signaling
Hippo signaling
apoptosis
Online Access:https://www.mdpi.com/1422-0067/22/20/11042

Internet

https://www.mdpi.com/1422-0067/22/20/11042

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