Cyclovirobuxine D inhibits the growth of osteosarcoma cells through the induction of autophagy flux arrest by promoting lysosomal acidification

Cyclovirobuxine D inhibits the growth of osteosarcoma cells through the induction of autophagy flux arrest by promoting lysosomal acidification

Osteosarcoma (OS) is an aggressive primary tumor with the highest incidence in children and adolescents. Natural plant compounds (NPCs) have long been promising resources in the field of antitumor drug discovery because of their high efficacy and low toxicity. Here, the aim of this study is to inves...

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Bibliographic Details
Main Authors: Shiqiong Liang, Liping Xie, Ziyun Li, Qiuping Lu, Lulu Zhang, Jiayu Wang, Haichao Xia, Lijuan Luo, Xiaoxuan Wang, Jinyong Luo
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Functional Foods
Subjects:
Cyclovirobuxine D
Osteosarcoma
Autophagy
Lysosome
Acidification
V-ATPase
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624002123

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http://www.sciencedirect.com/science/article/pii/S1756464624002123

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