Predictive value of intratumoral-metabolic heterogeneity derived from 18F-FDG PET/CT in distinguishing microsatellite instability status of colorectal carcinoma

Predictive value of intratumoral-metabolic heterogeneity derived from 18F-FDG PET/CT in distinguishing microsatellite instability status of colorectal carcinoma

Purpose/backgroundMicrosatellite instability (MSI) status is a significant biomarker for the response to immune checkpoint inhibitors, response to 5-fluorouracil-based adjuvant chemotherapy, and prognosis in colorectal carcinoma (CRC). This study investigated the predictive value of intratumoral-met...

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Bibliographic Details
Main Authors: Li Zhang, Yu Liu, Ying Ding, Yinqian Deng, Huanyu Chen, Fan Hu, Jun Fan, Xiaoli Lan, Wei Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Oncology
Subjects:
microsatellite instability
positron emission tomography/computed tomography
metabolic parameter
heterogeneity
colorectal carcinoma
immune-checkpoint inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1065744/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1065744/full

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