Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help

Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help

Abstract Tissue resident memory (Trm) CD8 T cells infiltrating tumors represent an enriched population of tumor antigen-specific T cells, and their presence is associated with improved outcomes in patients. Using genetically engineered mouse pancreatic tumor models we demonstrate that tumor implanta...

Full description

Bibliographic Details
Main Authors: Terry R. Medler, Gwen Kramer, Shelly Bambina, Andrew J. Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka R. Crittenden, Michael J. Gough
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33508-1

Internet

https://doi.org/10.1038/s41598-023-33508-1

Similar Items