Identifying chronic obstructive pulmonary disease from integrative omics and clustering in lung tissue

Identifying chronic obstructive pulmonary disease from integrative omics and clustering in lung tissue

Abstract Background Chronic obstructive pulmonary disease (COPD) is a highly morbid and heterogenous disease. While COPD is defined by spirometry, many COPD characteristics are seen in cigarette smokers with normal spirometry. The extent to which COPD and COPD heterogeneity is captured in omics of l...

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Bibliographic Details
Main Authors: Brian D Hobbs, Jarrett D Morrow, Xu-Wen Wang, Yang-Yu Liu, Dawn L DeMeo, Craig P Hersh, Bartolome R Celli, Raphael Bueno, Gerard J Criner, Edwin K Silverman, Michael H Cho
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Pulmonary Medicine
Subjects:
Chronic obstructive pulmonary disease
Gene expression
DNA methylation
Integrative omics
Clustering
Similarity network fusion
Online Access:https://doi.org/10.1186/s12890-023-02389-5

Internet

https://doi.org/10.1186/s12890-023-02389-5

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