Protein Tyrosine Kinase 7 (PTK7) Promotes Metastasis in Hepatocellular Carcinoma via SOX9 Regulation and TGF-β SignalingSummary

Background & Aims: Metastasis is found in most advanced hepatocellular carcinoma (HCC) patients, and it drives tumor recurrence and systemic failure. There is no effective treatment owing to its complex biological features. Many of the molecular drivers of metastasis are crucial players in n...

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Bibliographic Details
Main Authors: Tsz Lam Matthew Wong, Tin-Lok Wong, Lei Zhou, Kwan Man, James Purcell, Terence K. Lee, Jing-Ping Yun, Stephanie Ma
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22002107