Quantifying biochemical reaction rates from static population variability within incompletely observed complex networks.

Quantifying biochemical reaction rates within complex cellular processes remains a key challenge of systems biology even as high-throughput single-cell data have become available to characterize snapshots of population variability. That is because complex systems with stochastic and non-linear inter...

Full description

Bibliographic Details
Main Authors: Timon Wittenstein, Nava Leibovich, Andreas Hilfinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010183