Quantifying biochemical reaction rates from static population variability within incompletely observed complex networks.
Quantifying biochemical reaction rates within complex cellular processes remains a key challenge of systems biology even as high-throughput single-cell data have become available to characterize snapshots of population variability. That is because complex systems with stochastic and non-linear inter...
Main Authors: | Timon Wittenstein, Nava Leibovich, Andreas Hilfinger |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-06-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1010183 |
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