Durable remission related to CAR-T persistence in R/R B-ALL and long-term persistence potential of prime CAR-T

Durable remission related to CAR-T persistence in R/R B-ALL and long-term persistence potential of prime CAR-T

CD19-targeted chimeric antigen receptor T lymphocytes (CAR-T) has demonstrated a high proportion of complete remission in the treatment of relapsed refractory acute B cell lymphoblastic leukemia (r/r B-ALL). It is of great clinical significance to explore which factors will impact long-term disease-...

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Bibliographic Details
Main Authors: Li Shiqi, Zhang Jiasi, Chen Lvzhe, Xu Huailong, He Liping, Liu Lin, Zhang Qianzhen, Yuan Zhongtao, Shen Junjie, Chen Zucong, Zhang Yingzi, Wang Meiling, Li Yunyan, Wang Linling, Fang Lihua, Chen Yingnian, Zhu Wei, Li Yu, Luo Le, Wang Youcheng, Zhang Dingsong, Dong Yancheng, Yin Ping, Zhang Lihua, Li Xiaoping, Hu Xiaozhuang, Zheng Zhongzheng, Yang Zhi, Qian Cheng, Wang Sanbin
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
CAR-T
persistence
durable remission
acute lymphoblastic leukemia
memory T cell
long-term remission
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770523000281

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http://www.sciencedirect.com/science/article/pii/S2372770523000281

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