Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages

Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages

Abstract Background Cerebral microbleeds (CMB) are MRI-demonstrable cerebral microhemorrhages (CMH) which commonly coexist with ischemic stroke. This creates a challenging therapeutic milieu, and a strategy that simultaneously protects the vessel wall and provides anti-thrombotic activity is an attr...

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Bibliographic Details
Main Authors: Rachita K. Sumbria, Vitaly Vasilevko, Mher Mahoney Grigoryan, Annlia Paganini-Hill, Ronald Kim, David H. Cribbs, Mark J. Fisher
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Neuroinflammation
Subjects:
Phosphodiesterase 3A
Cerebral microhemorrhage
Cerebral microbleeds
Cilostazol
Cerebral amyloid angiopathy
Online Access:http://link.springer.com/article/10.1186/s12974-017-0885-7

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http://link.springer.com/article/10.1186/s12974-017-0885-7

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