Lysosomal sequestration of free and esterified cholesterol from oxidized low density lipoprotein in macrophages of different species
Macrophage foam cells of atherosclerotic lesions store lipid in lysosomes and cytoplasmic inclusions. Oxidized low density lipoprotein (oxLDL) has been proposed to be the atherogenic particle responsible for the free and esterified cholesterol stores in macrophages. Currently, however, there is a pa...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1998-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520325153 |