Efficient Heat Shock Response Affects Hyperthermia-Induced Radiosensitization in a Tumor Spheroid Control Probability Assay

Efficient Heat Shock Response Affects Hyperthermia-Induced Radiosensitization in a Tumor Spheroid Control Probability Assay

Hyperthermia (HT) combined with irradiation is a well-known concept to improve the curative potential of radiotherapy. Technological progress has opened new avenues for thermoradiotherapy, even for recurrent head and neck squamous cell carcinomas (HNSCC). Preclinical evaluation of the curative radio...

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Bibliographic Details
Main Authors: Oleg Chen, Soňa Michlíková, Lisa Eckhardt, Marit Wondrak, Adriana M. De Mendoza, Mechthild Krause, Damian D. McLeod, Leoni A. Kunz-Schughart
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
hyperthermia
radiation therapy
proteotoxic stress
spheroids
heat shock proteins (Hsps)
head and heck squamous cell carcinomas (HNSCC)
Online Access:https://www.mdpi.com/2072-6694/13/13/3168

Internet

https://www.mdpi.com/2072-6694/13/13/3168

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